Narrative review: indeterminate pulmonary nodules
نویسندگان
چکیده
منابع مشابه
Video Assisted Thoracic Surgery for Indeterminate Pulmonary Nodules
The approach to patients with indeterminate pulmonary nodules is poorly defined. Should every pulmonary nodule be biopsied, is needle biopsy adequate, and other questions are challenges. Video assisted thoracic surgery or thoracoscopy has added a new diagnostic possibility which is evaluated in this paper. Fifty-five patients underwent thoracoscopy for diagnosis of a solitary pulmonary nodule. ...
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To the Editor: Alexander et al. (Aug. 23 issue)1 report findings from a prospective, multicenter gene-expression classifier validation study that raises several questions. For the 265 indeterminate fine-needle aspirates they tested, the geneexpression classifier had a sensitivity of 92%, a specificity of 52%, a positive predictive value of 47%, and a negative predictive value of 93%. Why the ob...
متن کاملLocal molecular analysis of indeterminate thyroid nodules
BACKGROUND Thyroid nodules are common but only a minority are malignant. Molecular testing can assist in helping determine whether indeterminate nodules are suspicious for malignancy or benign. The objective of the study was to determine if the analysis of mutations (BRAF, NRAS, KRAS and HRAS) using readily available molecular techniques can help better classify indeterminate thyroid nodules. ...
متن کامل68Ga-DOTATATE PET/CT imaging of indeterminate pulmonary nodules and lung cancer
PURPOSE 18F-FDG PET/CT is widely used to evaluate indeterminate pulmonary nodules (IPNs). False positive results occur, especially from active granulomatous nodules. A PET-based imaging agent with superior specificity to 18F-FDG for IPNs, is badly needed, especially in areas of endemic granulomatous nodules. Somatostatin receptors (SSTR) are expressed in many malignant cells including small cel...
متن کاملSputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules.
PURPOSE The early detection of lung cancer in heavy smokers by low-dose CT (LDCT) can reduce the mortality. However, LDCT screening increases the number of indeterminate solitary pulmonary nodules (SPN) in asymptomatic individuals, leading to overdiagnosis. Making a definitive preoperative diagnosis of malignant SPNs has been a clinical challenge. We have demonstrated that sputum miRNAs could p...
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ژورنال
عنوان ژورنال: Current challenges in thoracic surgery
سال: 2022
ISSN: ['2664-3278']
DOI: https://doi.org/10.21037/ccts-20-113